LocalMotif 1.0
软件简介[Introduction]：
LocalMotif is a software tool for discovering transcription factor binding motifs in a collection of DNA sequences. The uniqueness of LocalMotif lies in its ability to discover motifs that occur localized in certain positions in the DNA sequences with respect to a biological landmark. A well known example is the TATA box motif which usually occurs 25 bp upstream of the transcription start site in eukaryotic systems.
Discovery of localized motifs is important in many contexts, but has become especially relevant in the analysis of high throughput sequencing ChIP-Seq data. ChIP-Seq can determine thousands of binding sites of a transcription factor (TF) genome-wide with a resolution of ~20bp. This makes it possible to discover not only the binding motif of the ChIP transcription factor but also the motifs of several other transcription factors that work cooperatively with the ChIP TF. LocalMotif can effectively discover such co-localized motifs in DNA sequences flanking the ChIP-Seq peaks.
Discovery of localized motifs is important in many contexts, but has become especially relevant in the analysis of high throughput sequencing ChIP-Seq data. ChIP-Seq can determine thousands of binding sites of a transcription factor (TF) genome-wide with a resolution of ~20bp. This makes it possible to discover not only the binding motif of the ChIP transcription factor but also the motifs of several other transcription factors that work cooperatively with the ChIP TF. LocalMotif can effectively discover such co-localized motifs in DNA sequences flanking the ChIP-Seq peaks.
下载地址[Download]：
注意事项[Notice]：
·中生网广告不少，不过都很老实，如果你乐意，请支持本站一下，如果打扰到了你敬请绕过。
·本站提供的软件包含破解补丁及注册码均是由网上搜集，若无意中冒犯了你权利，请联系21doll@163.com，本站立即改正！
·任何涉及商业盈利目的均不得使用，否则产生的一切后果将由你自己承担。
本类热门软件TOP10
全部热门软件TOP10